Yes, there’s an option on the Schedule tab under the “More” menu to “Hide empty columns.” When checked, this maximizes the screen space devoted to days and staff that actually have appointments or availability.
So you can see just work days, no matter if they don’t happen to be Monday through Friday — or even consecutive! Just set the view to “Week” and any days when you don’t work are automatically hidden so they don’t take up extra space on your schedule.
You can use “Hide empty columns” with multiple staff in separate columns, too. Then only staff with availability or appointments will show on the schedule, and anyone with the day off will be hidden. As you move forward or back in time, the staff who are scheduled to work on those days will appear automatically.